Trigeminal Neuralgia Caused by Nasopharyngeal Carcinoma with Skull Base Invasion - a Case Report

鼻咽癌併顱底轉移擬似三叉神經痛－病例報告

王致仁(Chih-Jen Wang) ； 洪純隆(Shen-Long Howng)

《The Kaohsiung Journal of Medical Sciences》 17卷12期 (2001/12) Pp. 630-632

https://doi.org/10.6452/KJMS.200112.0630

摘要

一位50歲女性，到本院腦神經外科求診，主訴：左側臉部疼痛，已經三個月，陣發性的尖銳疼痛，沿著左前額經由眼框周圍直到嘴角，持續數分鐘到數小時，理學檢查，在頭頸部，並未發現可觸摸的腫塊，核磁共振攝影檢查，顯示在咽喉部有侵襲性腫瘤，左側咽喉部侵犯，向上到左顳葉顱底及海綿竇，經由內視鏡切片檢查，證實為鼻咽癌，病人經放射線治療並投與5-FU,Cisplatin等化學療法，腫瘤獲得良好控制，兩年門診追蹤，未見腫瘤復發。

並列摘要

We report a case of nasopharyngeal carcinoma with skull invasion, whose chief complaint was left-sided facial pain, which mimicked trigeminal neuralgia, and in whom there was no palpable neck mass. The magnetic resonance imaging (MRI) revealed an infiltrated lesion with abnormal signal intensity in the left nasopharynx, involving the left retro- and parapharyngeal space. The lesion was pathology-proven through biopsy of the nasopharynx to be a non-keratinizing carcioma. The patient received 6000 rad radiotherapy combined with 5-Fluorouracil(5-FU) and Cisplatin, and has been well after 2 years’ follow-up.

並列關鍵字

nasopharyngeal carcinoma ； brain metastasis ； trigeminal neuralgia