- 期刊
Pure Red Cell Aplasia After ABO Major-mismatched Allogeneic Peripheral Blood Stem Cell Transplantation Successfully Treated with Plasma Exchange and Low-dose Steroid :Two Case Reports
異體骨髓幹細胞移植後血型不合引發純紅血球減少症以血漿交換及低劑量類固醇治療成功之病例報告
若您是本文的作者，可授權文章由華藝線上圖書館中協助推廣。
摘要
純紅血球減少症是異體骨髓幹細胞移植捐贈者及接受者紅血球血型不合的併症之一，抗紅血球凝集素環孢徽素之使用被認為和此症有關，但其機轉仍不明確。此類病人比其他無此併發症的病人必須接受較多的輸血，針對此症目前並沒有標準治療方法，我們提出兩個異體骨髓幹細胞移植後發生純紅血球減少症的病例，以血漿交換，及低劑量類固醇治療成功之案例，並加以討論。
並列摘要
Pure red cell aplasia (PRCA) is a complication of ABO-incompatible allogeneic stem cell transplantation. The mechanism is not well known, although the isoagglutinin titer before transplantation or cyclosporine use is considered to be the cause. Patients with this complication require more blood transfusions than those without it. There is no standard treatment. We report two cases of PRCA after allogeneic peripheral blood stem cell transplantation that were successfully treated with plasma exchange and low-dose steroid.
延伸閱讀
- Tsai, J. C., Lai, Y. H., Tsai, Z. Y., Chien, L. J., & Tsai, J. H. (1991). 基因合成人類生紅血球素治療血液透析病人貧血之臨床效果：給予方法，鐵含量狀態，和血清鋁濃度對治療反應之影響. The Kaohsiung Journal of Medical Sciences, 7(3), 126-135. https://doi.org/10.6452/KJMS.199103.0126
- Chang, Y. H., Lim, K. H., Lin, H. C., Chang, M. C., Chen, G. S., & Hsieh, R. K. (2010). 紅血球生成素引起之抗體導致的純紅血球再生不良以及用免疫抑制療法有效的治療此疾病：二則病例報告以及文獻回顧. 內科學誌, 21(6), 441-447. https://doi.org/10.6314/JIMT.2010.21(6).08
- Chuang, Y. B., Lee, K. F., Cho, C. H., Wan, Z. H., & Lai, X. Y. (2013). 血栓性血小板減少紫斑症－溶血性尿毒症候群：疾病發生論和血漿置換術治療. 內科學誌, 24(4), 299-308. https://doi.org/10.6314/JIMT.2013.24(4).08
- Lin, C. K., Wang, S. Y., Chen, L. Y., Liu, N. H., & Lin, J. S. (1991). 造血分化不良症候群：對核間橋樑與體外骨髓培養之研究. Journal of Medical Sciences, 12(1), 13-24. https://www.airitilibrary.com/Article/Detail?DocID=10114564-199108-201307080009-201307080009-13-24
- 邱世欣、張泰琮、彭及江、陳添享（1986）。以交換輸血治療自體免疫溶血性血合併異體免疫溶血性血成功之一病例報告。The Kaohsiung Journal of Medical Sciences，2(4)，265-269。https://doi.org/10.6452/KJMS.198604.0265