Reproducibility of Peripapillary Retinal Nerve Fiber Layer and Macular Retinal Thickness Measurements Using Optical Coherence Tomography

用光學同軸眼底斷層掃描儀測量視網膜神經纖維層及黃斑部視網膜厚度測量值的再現性

徐聖曜(Sheng-Yao Hsu) ； 童逸楨(I-Chen Tung) ； 許明木(Min-Muh Sheu) ； 蔡榮坤(Rong-Kung Tsai)

《The Kaohsiung Journal of Medical Sciences》 22卷9期 (2006/09) Pp. 447-451

摘要

探討用光學同軸眼底斷層掃描儀測量正常眼視神經乳頭周圍視網膜神經纖維層及黃斑部視網膜厚度的測量值，並評估測量值在不同檢查人員問的再現性。每位正常受檢者任選一眼，由三位具經驗的檢查者用光學同軸眼底斷層掃描儀測量受檢眼視網膜神經纖維層及黃斑部視網膜厚度，並分析比較平均厚度值及三位檢查者檢查結果的差異性。研究中39位受檢者共39眼，受檢者24位女性，15位男性，平均年齡30.4歲。檢查前瞳孔散大後的平均瞳孔直徑為7.4公匣。比較瞳孔散大後的厚度測量值，無論視神經乳頭周圍視網膜神經纖維層或黃斑部視網膜厚度，在三位具經驗檢查者問，並無顯著差異。用光學同軸眼底斷層掃描儀來測量正常眼視神經乳頭周圍視網膜神經纖維層及黃斑部視網膜厚度，在檢查者之間其測量值有好的再現性。

關鍵字

黃斑部 ； 光學同軸眼底斷層掃描儀 ； 瞳孔散大 ； 視網膜神經纖維層

並列摘要

We investigated the interoperator reproducibility of peripapillary retinal nerve fiber layer(RNFL) and macular retinal thickness measurements using optical coherence tomography (OCT) in healthy Taiwanese eyes. In this study, OCT-3 was used by three trained and experienced operators to measure peripapillary RNFL and macular retinal thickness in a randomly chosen single eye from each normal subject. Mean thickness levels and the differences in thickness measurements among the three operators were calculated and compared. The eyes of 39 subjects (24 females and 15 males) were enrolled. The mean age of the subjects was 30.4 ± 16.1 years (range, 11-46 years). The mean pupil diameter after pupillary dilation was 7.4±0.6 mm (range, 6-9 mm). Comparing peripapillary RNFL and macular retinal thickness measurements after pupillary dilation, there were no significant differences in: superior, inferior, temporal, and nasal peripapillary areas; 6 mm total macular volume and foveal thickness; and 1, 3 and 6 mm perifoveal areas among the three operators. In this study, OCT thickness measurements showed good interoperator reproducibility among three trained and experienced operators.

並列關鍵字

macula ； optical coherence tomography ； reproducibility ； retinal nerve fiber layer