The issue of patient safety has recently become more serious. Physical restraint is an important acute indicator in the Taiwan Quality Indicator Project (TQIP). This article discusses the common materials of physical restraint, wrong methods of physical restraint in the clinic, the steps for executing physical restraint, the principles and alternatives to restraint therapies, and the technology of physical restraint. The article could be used as a reference for future quality improvement efforts for physical restraint in clinical care.