The study aimed to examine the effectiveness of integrated cardiopulmonary nursing care model on patients' quality of life, postoperative pulmonary complications and readmission for those who received a coronary artery bypass surgery. A correlation study design was used with 72 subjects recruited from a cardiac surgery ward in a southern medical center. Patients completed the quality of life scale (SF-36) after they discharged monthly follow-up. Patients Basic attributes were as independent variables, and quality of life, pulmonary complications as the performance metrics. The results showed that the patients' quality of life after bypass surgery for 1 month was at medium level (mean 56.2 ± 10.5). The quality of life for patients who received coronary artery bypass surgery was influenced by age, length of stay, chronic illness, and pulmonary complications. The empirical data derived from this study can serve as a reference for clinical practice. In addition to cardiac rehabilitation, nurses tailored the care plans to individualized needs in order to facilitate the patients' physical, mental and social functions to an optimum health state.