- 期刊
轉譯科學－一個未來實證照護及醫學研究的重要趨勢
Introduction of Translational Health Science-An Important Future Trend in Evidenced-Based Health Care and Research
摘要
轉譯科學目前已成為國際間尤其是先進國家醫學研究的主流，各大經濟體均積極投資於轉譯科學的推動，以期更有效率與效益的結合醫學研究以及臨床照護。本文將簡介轉譯科學的概念以及其與臨床照護的關係。當應用醫學研究成果於臨床服務的過程中，經常會遭遇到的各種不同的困難與挑戰，一般稱為轉譯障礙；本文將介紹各國推動轉譯科學的策略，並透過澳洲Joanna Briggs Institute所勾勒的轉譯科學模型，完整闡釋在推動醫學研究落實於臨床照護的轉譯過程時，研究者、臨床專業人員與臨床服務使用者所遭遇的問題。同時討論如何應用系統性的策略設計，更有效率地克服上述的轉譯科學障礙。台灣在面對未來全球醫藥研究及醫療政策改變的趨勢時，在推動相關改革以因應轉譯科學的潮流時，文末也將簡介實證醫療照護所能扮演的角色。
並列摘要
The rapid development of medical, nursing and health science over the past fifty years has led to an enormous growth in knowledge. However, this burgeoning of knowledge has not necessarily been equated with an increase in the availability of knowledge to policymakers and clinical practitioners. Therefore, knowledge translation has been proposed by advance economies to tackle the prevailing failure in translating research into practice within health care. This involves the ongoing, iterative and interactive process of translating knowledge from research into clinical practice and policy through ethically sound application and complex interactions between researchers and the end users of research - including policy makers, managers and clinicians. There is a growing emphasis in implementing evidence into policy and practice across the globe. Of the existing gaps during the process of translating research into clinical practice, the barrier between clinical research and clinical action or policy is less addressed and can be easily overlooked. During the past few years, concepts of evidence-based medicine have been spread worldwide as well as in Taiwan. Taipei Veterans General hospital, as a leading institute in health service, medical research, and medical education in Taiwan, has also been involved in the advent of promoting evidence-based health care. However, even if it is a well-appreciated value for health professionals, the knowledge translation and related techniques have not been utilized in a systematic way. We will elucidate the gaps in the process of translational science by introducing the translational model proposed by the Joanna Briggs Institute, Australia and other western countries. Through the multi-dimensional approach in overcoming the barriers to the application of research evidence, the quality of our daily clinical care might be further improved.