巴金森氏症病人因腦細胞功能逐漸退化出現步態不穩、平衡感差之問題,若未能獲得控制或改善,可能因焦慮情緒產生憂鬱繼而影響其生活品質。已有研究揭示氣功有助於改善肌力並穩定平衡,又或能減輕巴金森氏症病人之焦慮、憂鬱或提升生活品質。本文旨在透過系統性文獻回顧暨統合分析方法,檢視氣功訓練對巴金森氏症病人在平衡功能、焦慮、憂鬱及生活品質之實質成效。搜尋12個資料庫,選取隨機控制試驗、符合納入及排除條件之中、英文文獻;共納入16篇研究文獻,採隨機效應模式(Random Effect Model)以標準化平均差(Standardized Mean Difference, SMD)估計合併效果量。結果顯示,氣功訓練可顯著改善巴金森氏症病人之平衡功能SMD為.880(11篇,95%CI[0.306,1.455],p=.003)、在焦慮改善之SMD為.357(5篇,95%CI[0.005,0.708],p=.047)、在憂鬱改善之SMD為.407(5篇,95%CI[0.074,0.740],p=.017)與提升生活品質之SMD為.563(9篇,95%CI[0.148,0.978],p=.008)。本研究結果發現氣功訓練能改善巴金森氏症病人之平衡功能、焦慮、憂鬱與提升生活品質,並歸納出可規劃每週至少3-5次,每次至少15-60分鐘,且持續5週以上的氣功運動處方作為實務之參酌。然而,本次分析之研究樣本數仍少,未來仍需更多研究驗證之。
The progression of Parkinson Disease can affect a patient's balance, leading to anxiety and depression, which can negatively affect their quality of life. Although previous studies have shown that qigong interventions may be effective in improving balance, reducing the risk of anxiety and depression, and improving quality of life in patients with Parkinson Disease, the results are inconsistent. Meta-analysis is required to clarify the findings. This systematic review and meta-analysis examined the effects of qigong on daily living, anxiety, depression, and quality of life in patients with Parkinson Disease. After a review of databases, 12 databases were included in this study. In total, 16 studies met the inclusion criteria and contained appropriate data for meta-analysis. Random-effects meta-analysis revealed that qigong had significant effects on functional balance (11 studies, standardized mean difference [SMD] = 0.880, 95% CI [0.306, 1.455], p = .003), anxiety (5 studies, SMD = .357, 95% CI [0.005, 0.708], p = .047), depression (5 studies, SMD = .407, 95% CI [0.074 ,0.740], p = .017) and health-related quality of life (9 studies, SMD = .563, 95% CI [0.148 ,0.978], p = .008). The findings indicate that qigong may improve the health-related quality of life of patients with Parkinson Disease and reduce their anxiety and depression levels. Patients with Parkinson Disease were instructed to perform qigong exercises three to five times per week, with each session lasting 15-60 minutes, for at least 5 weeks. The study sample was relatively small; additional studies with a larger sample are warranted.