Due to the fact that East Asia is close to the two largest drug resource areas in the world: ”Golden Triangle” in Southeast Asia and ”Golden New Moon” in middle Asia, it has been the center of drug trafficking in the world. Drug trafficking is rampant is this area. Smuggled drugs from this area, such as heroin, smuggled to North America, Europe, and the Asian countries. In recent years, a big change has already taken place in drug trafficking in the area. That is, synthetic drugs are now flooding rapidly, in addition to the serious problem of heroin flooding. Cross-border drug trafficking has become more and more rampant, and is now a new threat to humans. Taiwan is located in East Asia and drug problems come from abroad. The problems in Taiwan have become more and more serious in recent years because of the escalation of drug trafficking in East Asia. Therefore, the issues of understanding the trend of drug trafficking development in the area, strengthening international cooperation, and coming out with related counter measures, all demand immediate attention.