Comparative Study on Pain Responses to Intraarterial (Coronary and Femoral) and Intraperitoneal Injection of Algesic Agents in Dogs

動脈內及腹腔內發痛劑注射所引起的痛覺反應之比較研究

陳賢仁(H. J. Chen) ； 黃廷飛(T. F. Huang)

《The Chinese Journal of Physiology》 20卷3期 (1969/12) Pp. 173-181

摘要

將Bradykinin (BK)，氯化鉀，乙醯膽鹼(Ach)及Angiotensin注入狗心包膜內均能引起痛覺反應。注BK入冠狀動脈及股動脈所引起的痛覺反應之強度似乎無大差異。KCl注入冠狀動脈所引起的痛覺反應遠比注入股動脈爲顯著。注乙醯鹼入冠狀動脈及股動脈時，後者較易引起痛覺反應。

並列摘要

Chen, H. J. and T. F. Huang. Comparative study on pain responses to intraarterial (coronaray and femoral) and intraperitoneal injection of algesic agents in dogs. Chinese L Physiol., 20(3): 173-181, 1969-Pain responses to intrapericardial, intraperitoneal and intraarterial algesic agents were studied in unanesthetized dogs. Bradykinin, KC 1, angiotensin and acetylcholine evoked pain responses when they were injected into the pericardial sac, peritoneal cavity, coronary and femoral arteries respectively. Pain responses were comparable in degrees when bradykinin was injected into the coronary and femoral arteries. KC1 evoked more marked pain responses to intracoronary artery injection than those to intrafemoral artery injection, while pain responses to acetylcholine injection were the reverse of those to KCI injection.