Cardiac Arrhythmias of Vagal and Sympathetic Origin Induced by Carotid Occlusion

夾閉頸動脈所引起的迷走神經性及交感神經性心律不整

陳幸一(H. I. Chen) ； 李泰明(T. M. Lee) ； 蔡作雍(C. Y. Chai)

《The Chinese Journal of Physiology》 21卷2期 (1972/12) Pp. 117-124

摘要

淺度氯醛醣麻醉之貓，夾閉雙側頸動脈引發兩種不同之心律不整：一為迷走神經性，一為交感神經性。前者僅見於迷走神經完整之動物，且因注射阿托品而消失。後者可在迷走神經完整之動物身上引發，但切除減壓神經或迷走神經更易發生或加强原有之心律不整；且不為阿托品所影響。迷走神經性心律不整之型式多為偶發性或雙聯性之心房或心室異位脈，其發生之前伴有竇脈變慢，竇脈暫停或房室阻隔。交感神經性心律不整則通常發生於竇脈變快之後；其常見之型式，在迷走神經截斷之前為偶發性，三聯性或雙聯性之心房或心室早發脈；在迷走神經截斷後則為多發原性之心室異位脈或室脈變快。

並列摘要

Chen, H. I., T. M. Lee, and C. Y. Chai. Cardiac arrhythmias of vagal and sympathetic origin induced by carotid occlusion. Chinese J. physiol., 21(2): 117-124, 1972-Cardiac arrhythmias inuced by common carotid occlusion (CCO) in lightly anesthetized cats were found to be vagal and/or sympathetic in origin. Vagal arrhythmias which occur in vagus-intact animals were abolished by atropine. The arrhythmias were preceded with sinus bradycardia, sinus arrest or A-V block. Occasional or bigeminal atrial or ventricular ectopic beats were the most common forms to be observed. Sympathetic arrhythmias could be observed in vagus-intact animals, but were more readily elicited after section of the vagus or depressor nerves, and the arrhythmias were not affected by atropine. The arrhythmias were usually preceded with sinus tachycardia. When the arrhythmias occurred during intact vagus, they appeared usually in forms of occasional, trigeminal or bigeminal atrial or ventricular premature contractions. After vagotomy, they were mostly changed to multifocal ventricular extrasystoles or ventricular tachycardia. These findings suggest that vagal afferents may inhibit the sympathetic mechanism in producing cardiac arrhythmias, or activate the vagal component of the baroceptor reflex to produce cardiac arrhythmias.

並列關鍵字

Cardiac arrhythmias ； Common carotid occlusion ； Vagotomy