Potentiated Depression of Indirectly Evoked Twitch Tension of Rat Soleus Muscle Following Arterial Blood Occlusion in the Presence of Ketamine

電刺激坐股神經所導致的比目魚肌收縮經血管阻塞后所帶來的抑制作用可以在克太拉存在下增強

黃啟剛(K. K. Wong)

《The Chinese Journal of Physiology》 33卷4期 (1990/12) Pp. 329-333

摘要

本研究採用克太拉未能影響電刺激坐股神經所引發的比目魚肌收縮的劑量，發現克太拉能增強血管陰塞後所帶來的比目魚肌收縮被抑制的反應。這可能是因克太拉有可防止氧化磷酸化配對作用而增強這收縮抑制作用。

並列摘要

Wong, K. K. Potentiated depression of indirectly evoked twitch tension of rat soleus muscle following arterial blood occlusion in the presence of ketamine. Chinese J. Physiol. 33(4): 329-333, 1990. The presence of ketamine, in a dose insufficient to depress the indirectly evoked twitch tension of soleus muscle, was shown to significantly potentiate the depression of the indirectly evoked twitch tension following a 10-mm occlusion of the arterial blood to this muscle. Since ketamine was known to be an uncoupling agent in oxidative phosphorylation, it was possible that its uncoupling property potentiated the effect of the 1 0-mm blood occulsion to depress the indirectly evoked twitch tension of soleus muscle.

並列關鍵字

ketamine ； evoked twitch tension ； blood occlusion ； potentiated depression