- 期刊
Effect of Human Calcitonin on the Secretion of Luteinizing Hormone in Orchiectomized Rats
並列摘要
The effect of human calcitonin (hCT) on the secretion of luteinizing hormone (LH) was examined in castrated rats. Male rats were orchiectomized (Orch) 2 weeks before they were treated with a single bolus injection of gonadotropin-releasing hormone (GnRH,1 μk/kg of body weight), hCT (3.4 ng/kg), or the combination of GnRH and hCT through a right jugular vein catheter. Blood samples (0.5 ml each time) were collected immediately before (0-min) and then at 15, 30, 60, 120 and 180 min after hormone injection. Plasma LH concentration was measured with a radioimmunoassay technique. Plasma calcium concentration was determined in an automatic analyzer. hCT significantly diminished both the basal and GnRH-stimulated levels of plasma LH without any relation to the reduced plasma levels of calcium. These results clearly demonstrated a plasma calcium-unrelated inhibitory effect of hCT on LH secretion.
延伸閱讀
- Hsu, Y. H., Chang, C. W., Chen, M. C., Yuan, C. Y., Chen, J. H., Ma, J. T., Ueng, T. H., & Lu, S. Y. (2011). Carbendazim-Induced Androgen Receptor Expression Antagonized by Flutamide in Male Rats. 藥物食品分析, 19(4), 418-428. https://www.airitilibrary.com/Article/Detail?DocID=10219498-201112-201202170003-201202170003-38-48
- Saul, D., Kling, J. H., Kosinsky, R. L., Hoffmann, D. B., Komrakova, M., Wicke, M., Menger, B., & Sehmisch, S. (2016). Effect of the Lipoxygenase Inhibitor Baicalein on Muscles in Ovariectomized Rats. Journal of Nutrition and Metabolism, 2016(), 127-140. https://doi.org/10.1155/2016/3703216
- Li, S. M. (2004). A study of cyclophosphamide on dextran sulfate sodium-induced ulcerative colitis in mice [master's thesis, The University of Hong Kong]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0029-1812201200001435
- Mard, S. A., Maleki, M., Askari, H., & Naseri, M. K. G. (2014). Inhibition of Histamine-Stimulated Gastric Acid Secretion by Hydrogen Sulfide in Male Rats. Adaptive Medicine, 6(4), 157-160. https://doi.org/10.4247/AM.2014.ABE089
- 王家聆（2005）。Protective Effects of Histidine and Carnosine on Acetamionphen-Induced Hepatoxicity in Balb/cA Mice〔碩士論文，中山醫學大學〕。華藝線上圖書館。https://doi.org/10.6834/CSMU.2005.00088