- 期刊
Neural Connection from Hippocampus to Nucleus Accumbens and the Subpallidal Area and Their Contribution to Locomotor Activity
並列摘要
Neural connections from the hippocampus and nucleus accumbens to the subpallidal area have been implicated by behavioral observation. The locomotor activity recorded in an automated activity cage increased substantially after the bilateral injection of carbachol, a cholinergic agonist, into the dentate gyrus of the hippocampus, and this increase of activity was reduced significantly after the injection of glutamate antagonist into the nucleus accumbens. On the other hand, this hyperactivity elicited by the injection of carbachol was also reduced by the injection of GABA into the subpallidal area. In another observation, increased locomotor activity was recorded following the injection of dopamine into the nucleus accumbens. However, the increase of locomotor activity induced by dopamine was attenuated by the injection of GABA into the subpallidal area. These observations suggest that neural connections from hippocampus and nucleus accumbens to the subpallidal region may contribute to locomotor activity.
延伸閱讀
- Wainwright, S. R., & Galea, L. A. M. (2013). The Neural Plasticity Theory of Depression: Assessing the Roles of Adult Neurogenesis and PSA-NCAM within the Hippocampus. Neural Plasticity, 2013(), 562-575. https://doi.org/10.1155/2013/805497
- Wang, Y. C. (2020). Longitudinal analysis of functional connectivity for focused ultrasound-neuromodulation on different brain regions : A rat study [master's thesis, National Tsing Hua University]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0016-2502202114271198
- Coward, L. A., & Gedeon, T. D. (2016). Using the Change Manager Model for the Hippocampal System to Predict Connectivity and Neurophysiological Parameters in the Perirhinal Cortex. Computational Intelligence and Neuroscience, 2016(), 860-872. https://doi.org/10.1155/2016/8625875
- Tzeng, W. Y., Su, C. C., Sun, L. H., Cherng, C. G., & Yu, L. (2018). Synergistic Effects of Psychosocial Stress and Mild Peripheral Infection on Inducing Microglial Activation in the Hippocampal Dentate Gyrus and Long-Lasting Deficits in Hippocampus-Related Memory. The Chinese Journal of Physiology, 61(2), 106-117. https://doi.org/10.4077/CJP.2018.BAG569
- Jiang, Z., Wang, X. F., & Yue, G. H. (2016). Strengthened Corticosubcortical Functional Connectivity during Muscle Fatigue. Neural Plasticity, 2016(), 358-368-029. https://doi.org/10.1155/2016/1726848