Inhibitory Effect of Estrogen on Vascular Contraction From Male Rats of Different Ages

Y. F. Sun ； C. H. Yen ； Y. T. Lau

《The Chinese Journal of Physiology》 40卷2期 (1997/06) Pp. 79-83

並列摘要

In order to quantify the tremorine and cold tremor activity in unanesthetized rats,a newultrasonic motion transducer method was used.Both kinds of activity are reported as vibratory bodymotion that occurred between 18-32 Hz as determined by spectral analysis.The recorded signal wasanalyzed and its power spectrum was obtained through a fast Fourier transform operation.It was foundthat a negative linear relation occurs between shiver amplitude and ambient temperature(r=0.999).Anegative linear relation also occurs between metabolic rate and ambient temperature(r=0.997).Inaddition,a positive linear relation between metabolic rate and cold shiver exists(r=0.999).Bothtremorine(30 mg/kg,i.p.)and cold tremor(Ta=2-22℃)activity monitored by the ultrasonic methodwere completely abolished by premedication with 1 mg/kg atropine.Thus,it appears that the advantagesof this tremor detection method are that is non-invasive and non-contact.Therefore,the ultrasonicmethod provides a good choice for quantifying tremorine and cold tremor activity in unanesthetizedanimals during studies of thermoregulatory physiology or motor disorders.

並列關鍵字

Vascular Contraction ； Thoracic Aorta ； 17β-Estradiol ； Age