- 期刊
Influence of Intermittent Hypobaric Exposure on SOD and TBARS Levels in Trained Rats
並列摘要
Live high train low (LHTL) is a well-known training model in order to prepare for competitions. In this study, the thiobarbituric acid reacting substances (TBARS) levels and superoxide dismutase (SOD) activity were determined in heart, lung and muscle tissue of rats. They were intermittently exposed to hypobaric pressure of 523 mmHg, corresponding to an altitude of 3,000m, and they performed swim training at sea level. Two groups of male rats were trained to swim for thirty minutes a day and 4 days a week lasting 9 weeks. Two groups were exposed to hypobaria for 120 min a day and 4 days a week for 9 weeks in pressure cabin. In heart tissue, TBARS levels of normobaric trained (NbT) group was higher (P＜0, 05) than normobaric sedentary (control) group. TBARS levels of hypobaric trained (HbT) group was higher than control and hypobaric sedentary (Hb) groups (P＜0.001; P＜0.01, respectively). TBARS levels of lung tissue of HbT group was also higher than that of the same groups (control; P＜0.01, Hb; P＜0.05, respectively). In muscle tissue, TBARS levels of HbT group was higher than that of the sedentary groups (control; P＜0.001, Hb; P＜0.05, respectively). SOD activity of heart tissue of HbT group was higher (P＜0.001) than that of the other groups. In lung tissue, SOD activity of control group was lower than that of the other groups (HbT; P＜0.001, NbT; P＜0.01, Hb; P＜0.01, respectively). In muscle tissue, SOD activity of HbT group was higher (P＜0.01) than that of the control group. The results of our study suggest that intermittent hypobaric exposure may augment exerciseinduced oxidative stress in heart, lung and muscle of trained rats.
參考文獻
延伸閱讀
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