Odour Transduction in Olfactory Receptor Neurons

Jean-Pierre Rospars ； Yu-Qiao Gu ； Alexandre Grémiaux ； Philippe Lucas

《The Chinese Journal of Physiology》 53卷6期 (2010/12) Pp. 364-372

https://doi.org/10.4077/CJP.2010.AMM038

並列摘要

The molecular mechanisms that control the binding of odorant to olfactory receptors and transduce this signal into membrane depolarization are reviewed. They are compared in vertebrates and insects for interspecific (allelochemicals) and intraspecific (pheromones) olfactory signals. Attempts to develop quantitative models of these multistage signalling networks are presented. Computational analysis of olfactory transduction is still in its infancy and appears as a promising area for future developments.

並列關鍵字

olfactory receptors ； ionic channels ； OBPs ； pheromones ； computer models

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