The difference between the dominant and nondominant hands in the perception of vibration, temperature, and heat pain was compared between 26 dentists with long-term exposure to high-frequency vibration and 18 with short-term exposure. The dentists with long-term exposure had larger vibration threshold differences than those with short-term exposure, both for digit Ⅱ (exposed to high-frequency vibration) and for digit V (unexposed), whereas the temperature and pain thresholds were similar. The former group had neurological symptoms in the dominant hand more often than the latter. Vibration threshold differences of exposed digit Ⅱ and unexposed digit Ⅴ were higher for the symptomatic dentists than for the symptom-free dentists. Since the exposed and unexposed fingers were similarly affected, the neurological symptoms in the dominant hand of dentists with long-term exposure seem to have some other etiology than high-frequency vibration.