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Apoptotic Cells Induce the Wound Healing Via the Zebrafish Liver Cell Model

以斑馬魚肝臟細胞株探討凋亡細胞誘導傷口修復之影響

摘要


Reactive oxygen species is as an important role in the inflammation and wound healing. However, it is still unclear that the role of apoptosis responses in the inflammation and healing. In this paper, we try to hypothesize that the induced oxidative stress is as an alarm signaling to defend the pathogens in the inflammation response while the damage occurred.

並列摘要


活性氧物質或其他因子引發凋亡反應時,凋亡細胞作用於發炎反應和癒合的角色尚不清楚。本研究提出的假設認為,誘導氧化反應可做為斑馬魚肝臟組織警報信號,促使肝組織在發炎反應後進行修復功能。結果顯示,傷口損傷時,抑制活性氧物質的產生,將會抑制細胞攝入葡萄糖的反應,也會抑制鈣離子訊息的發生。

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