In order to raise the efficiency and decrease risk and cost in drilling work, top-driven drilling system is applied constantly in drilling operation, also it becomes a main equipment for highly difficult drill well. It owns the special character which it supplies the maximum safety and convenience what the traditional rotary drill does not have. The operators should realize the features and operation of top-driven drilling system before using it. It is applied in the difficult condition drilling work, it can rotate the drill pipe and circulate the hole when tripping out and in, also it can be back and forward reaming and pull the drill string through the tight spots, reducing the incidence of stuck pipe. The article introduces the top-driven drilling system's operation and application which it was used in two deep drilling difficult wells, its innovative benefits conquered the drilling difficulty in high temperature and pressure occurred in worst geology conditions, and drilling got to the target smoothly.