Amplification of coherent acoustic phonon oscillations in InGaN multiple-quantum-wells (MQWs) has been observed. After initiating the coherent acoustic phonon oscillation in InGaN MQWs with an ultraviolet (UV) femtosecond (fs) pulse, a second UV fs pulse was introduced into the MQWs to initiate another coherent oscillation. Through an interferometric analysis based on a simple harmonic oscillator theory, a large coherent amplification (3.5 dB) of the initial acoustic phonon oscillation was revealed.