The interactions of a proton (3.7 GeV) with an emulsion can reveal the behavior of the nucleon-nucleus interactions. Furthermore, the interactions of 4He (2.1A GeV) and 7Li (2.2A GeV) with an emulsion introduce adequately a manner-representing nucleus-nucleus interactions. On the other hand, a major part of this work concerns the target fragmentation process. Thus, the yields of the target fragmentation (heavily ionizing particles N(subscript h)) have been studied on the basis of a comprehensive analysis of the data in the literature. The complete destruction of Ag nuclei (heaviest target in the emulsion) is achieved at a limiting value of N(subscript h) (N(subscript h)≥28) for the nucleus-nucleus interactions. This study gives an indication of being a rich source of information on nuclear structure.