Nutrient Intake Risk Factors of Osteoporosis in Postmenopausal Women

影響更年期女性骨質疏鬆的營養攝取危險因子

Jeong-Seon Kim ； Sun-Young Lim ； Joo-Hak Kim

《Asia Pacific Journal of Clinical Nutrition》 17卷2期 (2008/06) Pp. 270-275

https://doi.org/10.6133/apjcn.2008.17.2.13

摘要

本研究評估停經後期女性飲食中營養素攝取與骨質疏鬆危險性之關係。骨質密度測量方式，在腰椎部位利用雙能量X光吸收儀測量獲得。問卷部分，請受過訓練的訪視者以有架構的問卷進行訪談，其中包含的資訊為：社會人口學變項、用藥及生育史、飲食攝取。研究樣本收集134位骨質疏鬆與137位沒有骨質疏鬆之受試者，年齡為52歲至68歲之間。各營養素攝取量劃分為四分位。以最低攝取量組當作參考組，將最高組與最低組相比較，計算出勝算比（oddsratio）及信賴區間。對骨質疏鬆的發生，總蛋白質攝取量之勝算比為1.47，動物性蛋白質為1.62，鈉為2.98。反之，植物性蛋白質之勝算比為0.42，鈣為0.72，鐵為0.68。本研究的發現指出在停經後女性中，適當的營養素攝取可能對於預防骨質疏鬆是重要的。

關鍵字

營養素 ； 飲食 ； 骨質疏鬆 ； 停經 ； 危險因子

並列摘要

This study was conducted to assess the association between dietary nutrient intake and osteoporosis risk in postmenopausal women. Bone mineral density was measured at the lumbar spine by dual-energy X-ray absorptiometry and a structured questionnaire was administered by a trained interviewer, which included information on sociodemographics, medical and reproductive history, and dietary intake. The study sample included 134 osteoporotic and 137 non-osteoporotic subjects between the ages of 52 and 68. Nutrient variables were classified into tertiles. Odds ratios and 95% confidence intervals (CI) were calculated which compared the highest tertile with the lowest tertile as a reference group. Odds ratios for osteoporosis were 1.47 (95% CI: 1.03 – 2.05) for total protein, 1.62 (95% CI: 0.51 – 3.92) for animal protein, and 2.98 (95% CI: 1.42 – 4.23) for sodium. Odds ratios for osteoporosis in the highest tertile were: 0.42 (95% CI: 0.23 – 0.83) for vegetable protein, 0.72 (95% CI: 0.51 – 0.90) for Ca, and 0.65 (95% CI: 0.49 – 0.88) for Fe, relative to the respective lowest tertile. These findings suggest that adequate nutrient intake may be important for prevention of osteoporosis in postmenopausal women.

並列關鍵字

nutrient ； diet ； osteoporosis ； menopause ； risk