High Fish Consumption in French Polynesia and Prenatal Exposure to Metals and Nutrients

法屬玻里尼西亞魚的高攝取量與胎兒時期的金屬與營養素暴露

Eric Dewailly ； Édouard Suhas ； Yolande Mou ； Renée Dallaire ； Ludivine Château-Degat ； René Chansin

《Asia Pacific Journal of Clinical Nutrition》 17卷3期 (2008/09) Pp. 461-470

https://doi.org/10.6133/apjcn.2008.17.3.15

摘要

法屬玻里尼西亞人攝取高量的魚，因此會暴露到海鮮食物相關的汙染物如汞或鉛，及營養素如碘、硒，及長鏈多元不飽和脂酸。胎兒的發展過程中對於污染物及營養素是敏感的，因此2005-2006年在法屬玻理尼西亞做一個橫斷性的研究，去評估胎兒時期經由魚類攝取而暴露到汙染物及營養素的情形。被納入的241名產婦均來自於法屬玻里尼西亞群島，且同意回答有關於魚類的攝取，並允許收集臍帶血以供金屬與營養素分析。除了鉛以外，所有的參數都被發現在臍帶血中具有高濃度。汞濃度平均為64.6nmol/L(或13μg/L)，範圍為0.25到240nmol/L。在這些樣本中，有82.5%血液汞的濃度超過US-EPA所訂的標準值5.8μg/L。鮪魚是魚類中提供汞暴露最多的。高量的硒及長鏈多元不飽和脂酸可能抵銷在法屬玻里尼西亞胎兒暴露到汞的潛在危險性。由於母親攝取高量的魚，玻里尼亞人的新生兒在胎兒時期即暴露到高劑量的汞。雖然硒及omega–3脂肪酸可能相抵汞的毒性，但是告知懷孕婦女當地魚種汞及營養素兩者的含量是重要的。

關鍵字

汞 ； n-3脂肪酸 ； 碘 ； 硒 ； 鉛 ； 新生兒

並列摘要

French Polynesians consume high quantities of fish and are therefore exposed to seafood-related contaminants such as mercury (Hg) or lead (Pb) and nutrients such as iodine, selenium and long chain polyunsaturated fatty acids (LC-PUFAs). As the developing foetus is sensitive to contaminants and nutrients, a cross-sectional study was conducted in French Polynesia in 2005-2006 to assess prenatal exposure to contaminants and nutrients through fish consumption. Two hundred and forty one (241) delivering women originating from all islands of French Polynesia were recruited and agreed to answer questions on fish consumption and gave permission to collect umbilical cord blood for metals and nutrients analyses. All parameters were found in high concentrations in cord blood samples except for lead. Mercury concentrations averaged 64.6 nmol/L (or 13 μg/L) with values ranging from 0.25 to 240 nmol/L. Of the sample, 82.5% had Hg concentrations above the US-EPA blood guideline of 5.8 μg/L. Tuna was the fish species which contributed the most to Hg exposure. High selenium and LCPUFAs may counterbalance the potential risk of prenatal exposure to Hg in French Polynesia. Due to the high fish consumption of mothers, Polynesian newborns are prenatally exposed to high doses of mercury. Although selenium and omega-3 fatty acids may counteract mercury toxicity, informing pregnant women on both the mercury and nutrient content of local fish species is important.

並列關鍵字

mercury ； n-3 fatty acids ； iodine ； selenium ； lead ； newborns