Validation of Prediction Equations for Estimating Resting Energy Expenditure in Obese Chinese Children

評定靜息能量消耗預測方程在肥胖華商兒童的效度

Dorothy FY Chan ； Albert M Li ； Michael HM Chan ； Kwan-So Hung ； Iris HS Chan ； Jane AT Yin ； Christopher WK Lam ； Fai-Fok Tai ； Edmund AS Nelson

《Asia Pacific Journal of Clinical Nutrition》 18卷2期 (2009/06) Pp. 251-256

https://doi.org/10.6133/apjcn.2009.18.2.14

摘要

Objectives: (1) To examine the validity of existing prediction equations (PREE) for estimating resting energy expenditure (REE) in obese Chinese children, (2) to correlate the measured REE (MREE) with anthropometric and biochemical parameters and (3) to derive a new PREE for local use. Design: Cross-sectional study. Subjects: 100 obese children (71 boys) were studied. Measurements: All subjects underwent physical examination and anthropometric measurement. Upper and central body fat distribution was signified by centrality and conicity index respectively, and REE was measured by indirect calorimetry. Fat free mass (FFM) were measured by DEXA scan. Thirteen existing prediction equations for estimating REE were compared with MREE among these obese children. Fasting blood for glucose, lipid profile and insulin were obtained. Results: The overall, male and female median MREEs were 7.1 mJ/d (IR 6.2-8.4), 7.3 mJ/d (IR 6.3-9.7) and 6.9 mJ/d (IR 5.6-8.1) respectively. No sex difference was noted in MREE (p=0.203). Most of the equations except Schofield equation underestimated REE of our children. By multiple linear regression, MREE was positively correlated with FFM (p＜0.0001), conicity index (p＜0.001) and centrality index (p=0.001). A new equation for estimating REE for local use was derived as: REE = (17.4*logFFM) + (11.4*conicity index) - (2.4*centrality index) - 31.3. The mean difference of new PREE-MREE was -0.011 mJ/d (SD 1.51) with an interclass correlation coefficient of 0.91. Conclusion: None of the existing prediction equations were accurate in their estimation of REE, when applied to obese Chinese children. A new prediction equation has been derived for local use.

關鍵字

肥胖 ； 兒童 ； 體脂分佈 ； 靜息能量消耗 ； 胰島素阻抗

並列摘要

Objectives: (1) To examine the validity of existing prediction equations (PREE) for estimating resting energy expenditure (REE) in obese Chinese children, (2) to correlate the measured REE (MREE) with anthropometric and biochemical parameters and (3) to derive a new PREE for local use. Design: Cross-sectional study. Subjects: 100 obese children (71 boys) were studied. Measurements: All subjects underwent physical examination and anthropometric measurement. Upper and central body fat distribution was signified by centrality and conicity index respectively, and REE was measured by indirect calorimetry. Fat free mass (FFM) were measured by DEXA scan. Thirteen existing prediction equations for estimating REE were compared with MREE among these obese children. Fasting blood for glucose, lipid profile and insulin were obtained. Results: The overall, male and female median MREEs were 7.1 mJ/d (IR 6.2-8.4), 7.3 mJ/d (IR 6.3-9.7) and 6.9 mJ/d (IR 5.6-8.1) respectively. No sex difference was noted in MREE (p=0.203). Most of the equations except Schofield equation underestimated REE of our children. By multiple linear regression, MREE was positively correlated with FFM (p＜0.0001), conicity index (p＜0.001) and centrality index (p=0.001). A new equation for estimating REE for local use was derived as: REE = (17.4*logFFM) + (11.4*conicity index) - (2.4*centrality index) - 31.3. The mean difference of new PREE-MREE was -0.011 mJ/d (SD 1.51) with an interclass correlation coefficient of 0.91. Conclusion: None of the existing prediction equations were accurate in their estimation of REE, when applied to obese Chinese children. A new prediction equation has been derived for local use.

並列關鍵字

obese ； children ； body fat distribution ； resting energy expenditure ； insulin resistance