The Relationship between Habitual Dietary Phosphorus and Calcium Intake, and Bone Mineral Density in Young Japanese Women: A Cross-sectional Study

日本年輕女性日常膳食磷與鈣攝取與骨密度之相關性

Sanae Ito ； Hiromi Ishida ； Kazuhiro Uenishi ； Kentaro Murakami ； Satoshi Sasaki

《Asia Pacific Journal of Clinical Nutrition》 20卷3期 (2011/09) Pp. 411-417

https://doi.org/10.6133/apjcn.2011.20.3.08

摘要

磷與鈣在骨骼健康上扮演著重要的角色。過去西方國家研究發現，低鈣與高磷攝取，會導致較低的鈣磷比，而對於骨骼密度狀態有負面的影響。本篇橫斷型研究目的，在探討441位日本年輕女性（18-22歲），其日常磷與鈣攝取情形及鈣磷比與骨密度之相關性。本研究並假設日本年輕女性相較於西方年輕女性有較低的鈣磷比。此外，本研究也嘗試釐清，飲食鈣與磷攝取量與血清或尿液鈣與磷之相關性，同時也檢測其中214位女性的血清副甲狀腺素與25（OH）D。結果發現，磷與鈣攝取及鈣磷比與尿液磷呈現顯著正相關。在調整了初經後年齡、身體質量指數及體能活動後，鈣攝取及鈣磷攝取比與橈骨遠端骨密度呈現顯著正相關，但與腰椎骨及股骨頸的骨質密度沒有顯著相關性存在。本篇研究結果指出，日本年輕女性之磷攝取對於骨質密度沒有顯著的負面影響，而鈣攝取與鈣磷比僅與某些特定部位之骨質密度有顯著的相關。

關鍵字

磷 ； 鈣 ； 骨質密度 ； 副甲狀腺素 ； 日本年輕女性

並列摘要

Phosphorus and calcium are essential for bone health. There is a concern that a low calcium/phosphorus intake ratio resulting from low calcium intake coupled with high phosphorus intake may have a negative effect on bone mineral status, especially in Western countries. The objective of this study was to examine cross-sectionally the influence of habitual phosphorus and calcium intake and the calcium/phosphorus intake ratio on the bone mineral density (BMD) in 441 young Japanese women (aged 18-22) whose calcium/phosphorus intake ratio was assumed to be lower than young Western women. We also ascertained the relationship between dietary intake and serum or urinary measurements of phosphorus and calcium. Parathyroid hormone (PTH) and 25-hydroxy vitamin D (25(OH)D) were also examined for 214 of the 441 subjects. Phosphorus and calcium intake and the calcium/ phosphorus intake ratio had significant positive correlations with urinary phosphorus. Calcium intake and the calcium/phosphorus intake ratio independently had positive and significant associations with BMD in the distal radius adjusted for postmenarcheal age, body mass index, and physical activity. There were no significant associations with BMD in the lumbar spine and femoral neck. These results indicate that in young Japanese women, phosphorus intake did not have a significantly negative effect on bone mineral density, and calcium intake and calcium/phosphorus intake ratio had a small but significant association only in a site-specific manner with BMD.

並列關鍵字

phosphorus ； calcium ； bone mineral density ； parathyroid hormone ； young Japanese women