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Iodine dietary supplements during pregnancy and neonatal thyroid stimulating hormone

本文正式版本已出版,請見:10.6133/apjcn.022018.02

摘要


Background and Objectives: Pregnant women are at particular risk of iodine deficiency due to their higher iodine requirements, however although Iodine is known to be essential for normal growth and brain development, therefore neonatal outcomes in mildly iodine deficient areas are a critical consideration. This study aimed to investigate whether iodine supplement use corresponded to prevention of iodine insufficiency in the neonate using neonatal TSH screening criteria. Methods and Study Design: Gippsland-based women aged ≥18 years, in their third trimester of pregnancy, provided self-reported information regarding their iodine supplement use and consent to access their offspring's neonatal thyroid stimulating hormone (TSH) screening data. 126 women consented to participate, with 111 women completing all components of this study. Results: Only 18.9% of participants followed the NHMRC recommendation of 150 μg/day iodine supplement. With 42.3% of participants not taking any supplements, or taking supplements with no iodine or insufficient iodine. The remaining women (38.7%) were taking supplements with doses of iodine much higher (200-300 μg) than the NHMRC recommended dose or were taking multiple supplements containing iodine. When correlating iodine intake to their neonates' TSH, no correlation was found. When iodine supplementation usage was categorised as below, equal to, or above NHMRC recommendations there was no significant difference in neonatal TSH. Conclusion: Despite NHMRC guidelines for iodine supplementation during pregnancy, many women were not taking the required iodine supplementation. However, the level of maternal iodine supplementation did not impact on their baby's neonatal TSH.

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