- 期刊
- Ahead-of-Print
Fast-track Improves Post-operative Nutrition and Outcomes of Colorectal Surgery: A Single-center Prospective Trial in China
加速康复外科改善结直肠癌患者术后营养状态及临床效果：中国的一项单中心、前瞻性研究
摘要
Fast-track (FT) has been shown to enhance post-operative recovery. The aim of this study was to compare the effects of FT and traditional nutrition on post-operative rehabilitation, as well as evaluate the feasibility of applying FT in nutrition management of colorectal surgery. A prospective and randomized controlled trial was performed. This study included 464 patients who underwent colorectal surgery. The patients were randomly assigned into an FT group and a traditional group. The nutritional risk screening (NRS 2002) score, post-operative recovery index and surgical complications were compared between the FT and traditional groups. The NRS 2002 score in the FT group was better than the traditional group (p＜0.05). Serum indicators for nutrition (HGB, ALB, A/G) and immune function (lymphocyte rate [LYMPH%], IgA, and CD4+) in the FT group were superior to those in the traditional group (p＜0.05) on post-operative day 5. The first time to aerofluxus, defecation, oral intake and ambulation in the FT group was shorter when compared to the traditional group (p＜0.05). The complication incidence was significantly lower in the FT group than in the traditional group (p＜0.05). In particular, the occurrence rate of anastomotic leakage was higher in the traditional group than in the FT group (0.5% vs 2.8%, p＜0.05). Taken together, these data suggest that FT management can improve the nutritional condition and outcomes of colorectal surgical patients.
並列摘要
Fast-track (FT) has been shown to enhance post-operative recovery. The aim of this study was to compare the effects of FT and traditional nutrition on post-operative rehabilitation, as well as evaluate the feasibility of applying FT in nutrition management of colorectal surgery. A prospective and randomized controlled trial was performed. This study included 464 patients who underwent colorectal surgery. The patients were randomly assigned into an FT group and a traditional group. The nutritional risk screening (NRS 2002) score, post-operative recovery index and surgical complications were compared between the FT and traditional groups. The NRS 2002 score in the FT group was better than the traditional group (p＜0.05). Serum indicators for nutrition (HGB, ALB, A/G) and immune function (lymphocyte rate [LYMPH%], IgA, and CD4+) in the FT group were superior to those in the traditional group (p＜0.05) on post-operative day 5. The first time to aerofluxus, defecation, oral intake and ambulation in the FT group was shorter when compared to the traditional group (p＜0.05). The complication incidence was significantly lower in the FT group than in the traditional group (p＜0.05). In particular, the occurrence rate of anastomotic leakage was higher in the traditional group than in the FT group (0.5% vs 2.8%, p＜0.05). Taken together, these data suggest that FT management can improve the nutritional condition and outcomes of colorectal surgical patients.
延伸閱讀
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- 錢曉暉、李濤、廖婧、黃鍇亮、曹麗勤（2022）。加速康復外科在老年結直腸癌腹腔鏡手術中的應用。鏡湖醫學，22(2)，15-16+56。https://www.airitilibrary.com/Article/Detail?DocID=P20230317001-N202303170013-00004
- Lin, Y. C., Liu, K. W., Chen, H. P., Chen, Y. J., Kao, Y. K., Song, L. C., & Chen, C. I. (2021). 同步放射及化學治療後達到臨床完全緩解的直腸癌患者之預後：區域醫院的經驗分享. 中華民國大腸直腸外科醫學會雜誌, 32(2), 80-86. https://doi.org/10.6312/SCRSTW.202106_32(2).11004