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Glycogen Hepatopathy in Children with Poorly Controlled Type 1 Diabetes
並列摘要
Introduction: Glycogen hepatopathy has been described in children with poorly controlled type 1 diabetes mellitus (T1DM). Diabetic patients with hepatomegaly and abnormal liver enzymes have often been assumed to have nonalcoholic steatohepatitis rather than glycogen hepatopathy. It is important to recognize and distinguish glycogen hepatopathy from nonalcoholic steatohepatitis as it impacts the management and long-term prognosis. Case Report: We describe four cases of children with poorly controlled type 1 diabetes mellitus who developed glycogen hepatopathy, and review the available literature. Conclusion: Pediatricians should raise awareness of this potentially reversible liver complication in children with poorly controlled T1DM. It has been suggested that diabetic patients with hepatomegaly and elevated liver enzymes be given a trial of improved glycemic control prior to more invasive investigation.
延伸閱讀
- Chen, C. S., & Liao, K. M. (2005). The Effect of Individualized Education on Glycemic Control for Diabetic Patients. 北市醫學雜誌, 2(5), 454-464. https://doi.org/10.6200/TCMJ.2005.2.5.06
- 張鳳梅、戴淑華、林成新、張慧真（2014）。Determinants of Severe Hypoglycemia in Patients with Type 2 Diabetes Mellitus。臺灣臨床藥學雜誌，22(2)，67-80。https://doi.org/10.6168/FJCP.2014.2202.01
- 李俊賢（2007）。Non-type 1 Diabetes Mellitus in Children-Some Controversial Issues。Acta Paediatrica Taiwanica，48(5_S)，1-5。https://doi.org/10.7097/APT.200711.0001
- Lo, F. S., Yang, M. H., Chang, L. Y., Ou, Y. C., & Van, Y. H. (2004). Clinical Features of Type 1 Diabetic Children at Initial Diagnosis. Acta Paediatrica Taiwanica, 45(4), 218-223. https://doi.org/10.7097/APT.200408.0218
- Lee, S. L., Lo, F. S., Lee, Y. J., Chen, B. H., & Wang, R. H. (2015). Predictors of Glycemic Control in Adolescents of Various Age Groups With Type 1 Diabetes. The Journal of Nursing Research, 23(4), 271-279. https://doi.org/10.1097/jnr.0000000000000096