Rapid Diagnosis of Sinonasal Cancer in an Anticoagulated Patient: Outpatient Clinical Use of a Gelatinthrombin Matrix (Floseal) for Hemostasis Following Endonasal Tumor Biopsies

Shaun J Kilty

《International Journal of Case Reports and Images (IJCRI)》 2卷11期 (2011/11) Pp. 10-13

https://doi.org/10.5348/ijcri-2011-11-65-CR-3

並列摘要

Introduction: The purpose of this case report is to describe the use of gelatin-thrombin matrix (Floseal) for hemostasis to control severe nasal bleeding following endonasal biopsies in an elderly patient receiving anticoagulant therapies. Case Report: An Br-year-old woman with advanced Alzheimer's disease presented with rapid onset of midfrontal swelling, pain and orbital hypertelorism. Profuse bleeding occurred following tumor biopsies in the outpatient clinic which was controlled in less than five minutes with a single administration of Floseal. The pathologic diagnosis was diffuse large B-cell lymphoma and treatment was initiated within the week. There was no recurrence of bleeding following this single treatment. The use of Floseal safely and economically allowed for rapid diagnosis and treatment of this sinonasal cancer without the need to stop and restart anticoagulation therapy in an elderly patient with dementia. Conclusion: The outcome from the clinical management of this case suggests that this treatment approach may be a model for use in the rapid diagnosis of sinonasal pathology in the outpatient clinic even in the setting of anticoagulation.

並列關鍵字

Floseal matrix ； Hemostasis ； Biopsy ； Anticoagulants ； Diagnosis ； Warfarin ； Aspirin ； Paranasal sinuses