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Recurrent Opportunistic Infections in a Post-Transplant Lymphoma Patient

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Introduction: Infections and graft-versus-host disease (GVHD) are the most notable problems after allogeneic stem cell transplantation (Allo SCT). Case Report: A 50-year-old patient underwent an Allo SCT for transformed follicular lymphoma (t-FL). Transplant course of the patient was complicated by GVHD and recurrent, severe, opportunistic infections including pneumonia caused by two fungal pathogens simultaneously, recurrent bacteremia with no apparent source, septic arthritis caused by an unusual pathogen and eventually developed progressive multifocal leukoencephalopathy (PML). Conclusion: This case illustrates the diversity of opportunistic infections affecting patients undergoing Allo SCT and the complexity involved in diagnosis and treatment of such infections.

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