- 期刊
- OpenAccess
Lupus Associated Hepatitis in Active Lupus Nephritis Patient: A Case Report
並列摘要
Introduction: Systemic lupus erythematosus and autoimmune hepatitis (AIH) both are autoimmune disease causing inflammation of the liver. It is important to differentiate lupus hepatitis from AIH for diagnosis, treatment and prognosis of the disease. Case Report: Herein, we report a case of a 17-year-old female with a two-year history of multiple joint pain, sixmonth history of swelling, rash, mouth ulcers and a 15-day history of jaundice. An investigation revealed positive antinuclear antibody, positive anti-DsDNA, low serum C3, C4, very high serum bilirubin, high SGOT/SGPT and nephrotic range proteinuria. Antibody tests for autoimmune hepatitis were negative. Renal biopsy showed focal proliferative lupus nephritis. Liver biopsy was suggestive of lupus-hepatitis. Jaundice responded to steroid therapy dramatically. Conclusion: Lupus associated hepatic disease must be differentiated from hepatitis caused by drugs, toxins, viral and other autoimmune diseases. Liver histology may be necessary to confirm a diagnosis.
延伸閱讀
- Kau, C. K., Lu, L. Y., Hu, J. C., Tseng, J. C., Wang, J. S., & Cheng, H. H. (2004). Systemic Lupus Erythematosus with Lupus Nephritis and Renal Thrombotic Microangiopathy: A Case Report. Formosan Journal of Rheumatology, 18(1&2), 47-55. https://doi.org/10.6313/FJR.2004.18(1-2).06
- 曾雋揚、王怡寬（2018）。The New Management of Lupus Nephritis。腎臟與透析，30(4)，193-195。https://doi.org/10.6340/KD.201812_30(4).0006
- Ponticelli, C. (2005). Treatment of Proliferative Lupus Nephritis. Acta Nephrologica, 19(2), 47-52. https://www.airitilibrary.com/Article/Detail?DocID=10131671-200504-19-2-47-52-a
- Chang, H. C., Chen, C. C., Chen, H. Y., Liou, S. W., & Woung, L. C. (2008). Adult Onset Tubulointerstitial Nephritis and Uveitis Syndrome-A Case Report. 中華民國眼科醫學會雜誌, 47(4), 443-448. https://doi.org/10.30048/ACTASOS.200812.0008
- Bansal, R., Policar, M., & Mehta, C. (2010). Acute Hepatitis B and Acute HIV Coinfection in an Adult Patient: A Rare Case Report. Case Reports in Medicine, 2010(), 117-119-221. https://doi.org/10.1155/2010/820506