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Introduction: Pseudoxanthoma elasticum (PXE) is a rare genetic disorder that mainly involves the skin, eyes, and cardiovascular system. Case Report: We reported a case of pseudoxanthoma elasticum which involves axillae, neck, abdomen and thighs, together with angioid streaks of fundi, but without cardiovascular events. Skin biopsy specimen was taken and was stained with hematoxylin and eosin (H&E) that revealed clumping and fragmentation of elastic fibers. Conclusion: These features confirmed histopathological diagnosis of PXE.

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