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Diagnosis and management of nephrotic syndrome in an adult patient: A case report

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Introduction: Nephrotic syndrome is a disorder characterized by proteinuria >3.5 g/24 hr, hypoalbuminemia <3 g/dL, and peripheral edema. The underlying etiology of the condition is influenced in large part by the age of the patient. In children under the age of 16, a large majority of cases are secondary to minimal change disease, whereas in adults the causes are more varied to include focal segmental glomerulosclerosis and membranous nephropathy. Case Report: A 68-year-old male with nephrotic range proteinuria who required workup with laboratory studies, immunological screening, and both light microscopy as well as electron microscopy to arrive at a diagnosis of minimal change disease. Conclusion: Also included is a review of previously published studies regarding minimal change disease and its association with non-Hodgkin lymphoma in the adult population, along with a discussion of current treatment approaches and a comparison of their efficacies.

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Adult Change Minimal Nephrotic Proteinuria

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