Introduction: In Senegal, West Africa, the overall prevalence of schistosomiasis varies from 0.3 to 1%. A major focus of schistosomiasis urogenital is known around the banks of the Senegal River where the average infestation rate reached 71.8%. Vulvar location is rare, the case of uro-digestive is even more so. Case Report: It was a girl aged 9, from a village situated on the banks of the Senegal River, received for swollen labia lasting for three years. There was a notion of contact with the river water. At dermatological examination, she had an itchy swelling of the large labia, small labia, clitoris, the groin with a palpation papulonodular, fibrous. There was hyper eosinophilia. Dermal histology showed under an acanthotic epidermis, a granulomatous inflammatory reaction around the dermis of an infestation of viable eggs of Schistosoma species terminal spur characteristic of Schistosoma haematobium. The abdominalpelvic ultrasound revealed bilateral ureteral hydronephrosis The computed tomography urography without product injection noted an irregular parietal calcification of the bladder, ureters under pyelics, urethra, rectum, sigmoid, and the left colon with segmental dilatation of the ureters. She was put under praziquantel (40 mg/kg in two spaced taken 15 days). The outcome was favorable with a clear regression of swelling after one month. Resection of residual disease was made. Conclusion: We reported a vulvar bilharzia, remarkable by a clinical presentation, an urogenital tract case and the multidisciplinary management.