Synchronous carcinoma breast with renal cell carcinoma: A case report

Tej Prakash Soni ； Sajal Goel ； Lalit Mohan Sharma ； Anil Kumar Gupta ； Shantanu Sharma ； Ravindra Gothwal

《International Journal of Case Reports and Images (IJCRI)》 7卷11期 (2016/11) Pp. viii+720-723

https://doi.org/10.5348/ijcri-2016125-CR-10713

摘要

Introduction: Incidence of double malignancy (synchronous or metachronous) has increased significantly. Renal cell cancer or Breast Cancer as second primaries are reported in the literature, but synchronous carcinoma breast with renal cell carcinoma is extremely rare. We are reporting a case of carcinoma breast with synchronous renal cell carcinoma. Case Report: A 38-year-old female was investigated for a lump in right breast. Biopsy from breast lump was reported as infiltrating duct carcinoma. Metastatic workup revealed a large mass at lower pole of right kidney. Right MRM and right radical nephrectomy were done for synchronous carcinoma breast and renal cell carcinoma. Conclusion: Genetic predisposition, tobacco, HPV, improvement in survival and long term surveillance after first primary cancer treatment, history of radiation or chemotherapy can be associated with second cancer but exact cause of second cancer is still unknown. Larger studies and research is warranted as the risk of double malignancy has been increased substantially. The plausible mechanisms behind the synchronous cancers have to be investigated.

關鍵字

Carcinoma breast ； Rare ； Renal cell carcinoma ； Synchronous