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精神分裂症患者血清麩氨草酸轉胺酶之變化

The Change of Serum Glutamic Oxaloacetic Transaminase in Schizophrenia

摘要


SGOT (Serum glutamic oxaloacetic transaminase) was measured in 102 schizophrenic inpatients (M:85, F:17, mean age: 24.65±7.75) and 87 non-psychotic inpatients (all males, mean age: 24.24±8.85) in their first morning of hospitalization. 12 schizophrenics (11.7%) and 2 non-psychotics (2.30%) had elevated SGOT (40U/ml), the mean value being 25.66±1.48 and 21.40±0.88U/ml respectively. Both the percentage of elevation and the mean value of SGOT were significantly higher in schizophrenic group than that in non-psychotic group (P<0.01 & P<0.02). In schizophrenic group, the elevation of SGOT was significantly correlated with the degree of degree of activity (P<0.0025) but not so with hallucination, delusion and disturbance of association. Divided by the subgroup of schizophrenia, the percentage of elevation of SGOT in other type (catatonia, simple, schizoaffective & undifferentiated) was significantly higher than that of paranoid & hebephrenic (P<0.5). The mean value of SGOT in each subgroup had no significant difference. In addition, both the percentage of elevation and the mean value of SGOT had no significant correlation with the duratin of the psychoses.

關鍵字

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並列摘要


SGOT (Serum glutamic oxaloacetic transaminase) was measured in 102 schizophrenic inpatients (M:85, F:17, mean age: 24.65±7.75) and 87 non-psychotic inpatients (all males, mean age: 24.24±8.85) in their first morning of hospitalization. 12 schizophrenics (11.7%) and 2 non-psychotics (2.30%) had elevated SGOT (40U/ml), the mean value being 25.66±1.48 and 21.40±0.88U/ml respectively. Both the percentage of elevation and the mean value of SGOT were significantly higher in schizophrenic group than that in non-psychotic group (P<0.01 & P<0.02). In schizophrenic group, the elevation of SGOT was significantly correlated with the degree of degree of activity (P<0.0025) but not so with hallucination, delusion and disturbance of association. Divided by the subgroup of schizophrenia, the percentage of elevation of SGOT in other type (catatonia, simple, schizoaffective & undifferentiated) was significantly higher than that of paranoid & hebephrenic (P<0.5). The mean value of SGOT in each subgroup had no significant difference. In addition, both the percentage of elevation and the mean value of SGOT had no significant correlation with the duratin of the psychoses.

並列關鍵字

SGOT Schizophrenia

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