Mitral Valve Prolapse and Infective Endocarditis

二尖瓣脫垂症（Mitral valve prolapse）為最普通的心臟瓣脫病變。統計上其發生率在5－15%之間，以女性為多。以前的報告都提及它的發生率與年齡和體型都有密切的關係。但由二尖瓣脫垂而引起嚴重二尖瓣閉鎖不全（Mitral regurgitation MR）則好發於男性及老年的病患。國外文獻亦論及二尖瓣脫垂與進行性的二尖瓣閉鎖不全、細菌性心的膜炎、腦栓塞及瘁死有關。我們在亞東醫院自1981年12月至1988年5月間一共收集了96位二尖瓣脫垂的病例，其中包括51位男性，45位女性，平均年齡為31.4歲（由11至62歲），其中9位經心臟超心波及心音圖診斷為二尖瓣脫垂及二尖瓣閉鎖不全（收縮期全雜音Pansystolic murmur PSM），這9位病患中的4位曾併發有心內膜炎（Infective endocarditis），其中3位是年青女性，其體重（Quetelet's index）都少於20 Kg/m^2。結論，年青的二尖瓣脫垂女性病患與二尖瓣閉鎖不全，體重較輕者和併發心內膜炎有關。而年齡單獨因素並不是與心內膜炎直接有關。

關鍵字

二尖瓣脫垂；二尖瓣閉鎖不全；收縮期全雜音

並列摘要

Mitral valve prolapse (MVP) has been described as the most common diagnosed valvular cardiac abnormality with prevalence estimates varying from 5-15% of patients in general population with predominate in female. It's relation to age and body habitus has been well studied. Severe mitral regurgitation (MR) caused by MVP is more common in man and old aged patients. Many studies have also suggested that MVP is associated with progressive mitral regurgitation, bacterial endocarditis, cerebral emboli, and sudden death. We collected 96 cases of MVP from December 1981 to May 1988 at Far Eastern Memorial Hospital (FEMH). Included 51 males, and 45 females, with a mean age of 31.4 years (range 11 to 62). Nine cases were confirmed to have MVP and MR (pansystolic murmur) by echocardiogram and phonocardiogram. Four of them had clinical manifestation of infective endocarditis (IE) with 3 case's Quetelet's index less than 20 kg/M^2. We found that there is a good relation between MVP with MR, low body weight and infective endocarditis. Age factor is independent to IE in these cases.

並列關鍵字

Mitral valve prolapsed ； Infective endocarditis ； Pansystolic murmur

國際替代計量

Mitral Valve Prolapse and Infective Endocarditis

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