透過您的圖書館登入
IP:3.22.51.241
  • 期刊
  • OpenAccess

Autoantibody Complicating Multiple Alloantibodies in a Patient with Massive Transfusion

白體抗合併多種異體抗體之病例報告

摘要


一名22歲女性在美國遭遇車禍,受傷極為嚴重,需要大量輸血,她在當地接受了六個單位的全血,當時並無任何輸血反應。近三個月內,她沒有再接受輸血,住院後之抗體普檢試驗發現有自體及異體抗體,經抗體鑑定証實有四種特異性異體抗體:即抗-E、-JK^a抗-K及抗-KP^a,推測此異體抗體係自車禍後急救時大量輸血所致。據統計K及KP^a抗原在中國人中未曾被發現,所以抗-K及抗-Kp^a必定是由於曾經輸過白種或黑種人的血液而引起。多種異體抗體的鑑定是對血庫工作的一種挑戰,而合併自體抗體更增加抗體鑑定的困難度。茲將該病例之檢驗過程加以分析及討論。

關鍵字

自體抗體 異體抗體

並列摘要


A 22 years old female suffered from a car accident with multiple injuries and head contusion. She received emergency transfusion of 6 units of whole blood in the United States. Antibody screening revealed autoantibody and four alloantibodies, namely, anti-E, -Jk^a, -K and -Kp^a. Alloantibodies were induced by emergency transfusion. K and Kp^a antigens are virtually unknown in Chinese populations and anti-K and -Kp^a must be induced by a blood transfusion from Caucassians or Blacks, Multiple alloantibodies identification is a challenge to blood bank and autoantibodies add difficulty in trouble shooting. The immunohematological condition of this special case is analysed and discussed.

延伸閱讀