一例子宮腺瘤樣腫瘤之免疫組織化學觀察－病例報告及組織來源初探

Immunohistochmical Study of an Adenomatoid Tumor of the Uterus: Report of a Case and Review of Literature

曹唐義(Tang- Yi Tsao) ； 曾暉華(Hui-Hwa Tseng) ； 杜炎昌(Yen-Chang Tu)

《Journal of Medical Sciences》 9卷5期 (1989/10) Pp. 365-372

摘要

子宮腺腫瘤樣腫瘤為子宮罕見之良性腫瘤，其組織來源廣被爭議，大部份的學者均認為是源自間皮細胞。本病例報告－結節狀但周界不清楚的子宮腫瘤，經病理切片證實為典型之子宮腺瘤樣腫瘤。另以過氧化氫酶標示的免疫組織化學觀察，發現Keratin僅存在於腺瘤樣狀及血管瘤樣狀的管腔襯裡細胞中，FactorvIII僅存於血管內皮細胞內。且所有腫瘤組織內並無CEA的存在。由以上結果推斷，此腫瘤可能源自間皮細胞。

關鍵字

子宮腺瘤樣腫瘤

並列摘要

Adenoma toid tumor is a rare benign tumor of the uterus. The histogenesis of adenomatoid tumor has been a source of controversy. Recent an immune histochemical study of most investigators favor a mesothelial derivation. A nodular mass was identified from the uterus of a 39-year-old female. The lesion was diagnosed as adenomatoid tumor based on pathological examination. We utilized the immune peroxidase antiperoxidase staining including keratin, CEA and factor-VIII-related antigen, to elucidate the origin of the tumor. The evidence from the staining suggests that the adenomatoid tumor represents a form of an essentially mesothelial lesion. We reported one case herein, and, the literature regarding the morphology and histogenesis of this tumor was also reviewed.

並列關鍵字

Adenomatoid tumor ； Keratin Factor- VIII related Ag ； CEA