減壓病之組織病變研究

對潛水人員而言，減壓病為最常發生之疾病，其造成原因為潛水人員減壓或上升時，組織和血管內之氣泡形成和變大，引發症狀產生。為了解氣泡對組織之傷害，而從事本研究，共使用3隻兔子為實驗對象，其體重為2.5～3.0公斤，4月大，其中1隻為未經加壓－減壓程序變化之對照組（A組）；另2隻則將其放入高壓艙內，將其以每分鐘60呎加壓至170呎（約6.2大氣壓），停留1小時後，以每分鐘85呎速度直接上升至水面，以引發減壓病發生，為實驗組（B組），分別觀察二組於加壓前後肉眼及顯微鏡下之病理變化比較。本研究之目的，在於顯示急性期減壓病其肺臟、心臟、肝臟、腎臟、胃、腸、骨骼、腦部及血管組纖之病理變化。國內潛水人員常忽略了水下減壓停留，希望藉由此研究報告能了解氣泡對組織之傷害。

關鍵字

減壓病；氣泡；加壓－滅壓程序；大氣壓

並列摘要

For divers, the decompression sickness is the most common disease. Its primary cause is the formation and growth of bubbles within tissues or blood. Decompression sickness develops after the human being hue commenced decompression or ascent. In this study three rabbits, 2.5- 3.0 kilograms in weight and four months old, which were divided into two groups, one was the control group and the other two were experimental group. The control rabbit was autopsy at sea level atmosphere with no experience of compression-decompression procedures. The experimental rabbits were compressed for one hour at 170 feet (6.2 atmosphere, ATA) in the hyperbaric chamber, then were quickly decompressed to sea level pressure in two minutes. During the compression-decompression procedures, we observed the rabbits activity and behavior change as compared with the control rabbit. The purpose of this study is presented to show that in an acute stage of decompression sickness with the pathological lesion in various organs. The pathological lesions included lung, liver, heart, kidney, G-I tract, skeletal system, brain and blood vessel etc. In our country, divers always ignored underwater decompression stop. We hope that through this study, our diver can understand the gas bubble effect in organs and establish the accurate diving knowledge.

並列關鍵字

Decompression sickness (DCS) ； Gas bubble ； Compression-decompression procedures ； Atmosphere (ATA)

國際替代計量

減壓病之組織病變研究

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