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系統性紅斑狼瘡合併結核性腦膜炎-病例報告

Systemic Lupus Erythmatosus with Tuberculous Meningitis-A Case Report

摘要


在治療系統性紅斑狼瘡病患最麻煩的問題,就是其本身容易併發嚴重感染;但是屬於結核感染則不常見,在以往的報告中約有5%的發生率。而在結核感染中,屬於結核腦膜炎則更為罕見。本院報告一例系統性紅斑狼瘡合併結核腦膜炎且併發水腦症及腦血管梗塞,處理如此複雜的病人是相當棘手的。因為早期診斷,早期治療與癒後及存活率有密切相關性,所以假若在臨床病程上相符於結核腦膜炎,雖缺乏組織或檢驗證實,果斷地嚐試抗結核藥物是被允許的。

並列摘要


The high incidence of serious infections is one of the most disturbing problems in the management of patient with SLE. In spite of an increasing incidence of infection, an association between tuberculosis and SLE has been noted infrequently. SLE-associated tuberculosis aws previously reported which gives rise to a prevalence rate of 5%. However SLE-related tuberculous meningitis was rarely reported in the past. We reported a case with SLE-related tuberculous meningitis complicated with hydrocephalous and cerebral infarction. It is very difficult to deal with such a complicated case. The survival rate is strongly related to early diagnosis and early treatment Although patients with a clinical course compatible with tuberculous meningitis lacking in histological or laboratory confirmation, a judicious trial of antimycobacterial drug therapy is probably indicated.

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