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出生後新生兒腎功能發育之比較
Development of Renal Function Compared in Newborn Infants
摘要
33名出生1～2天大及該嬰兒為6～7天大之正常足月新生兒為研究對象，藉對其血液及尿液生化之改變，進行腎功能發育之分析比較中發現；嬰兒隨出生年齡之增加，除尿鈣有減少外，尿液中無機磷、鈉、氯、鉀與肌酸酐則均隨年齡之增加而其廓清率（clearance）也增加（p＜0.05）。而血清中除肌酸酐降低外，血鈣、無機磷則增加（p＜0.05）。以上之結果顯示；隨年齡而增加之腎血流及尿（流）量不僅與肌酸酐、鈉、氯、鉀在尿液之廓清率增加有關外，也為血中肌酸酐降低之重要因素。而嬰兒對奶中鈣、無機磷等之攝取量增加則或許是除副甲狀腺荷爾蒙及維生素D外對血液與尿液中鈣、無機磷影響之另一重要因素。
並列摘要
Renal function was studied in 33 healthy 1-2-day-old and 6-7-day-old full-term newborn infants. Urinary calcium excretion is reduced, but there are increases of clearance (excretion) of urine creatinine, sodium, chloride, potassium and phosphorus with increasing age (p＜0.05). There is decrease of serum creatinine, but increases of calcium and phosphorus (p＜0.05). It is suggested that renal blood flow and ruine flow rate should not only relate to low serum creatinine also relate to induce clearance (excretion) of urine creatinine, sodium, potassium and chloride. Intake of calcium, phosphorus from formula milk may be other important factors responsible to homeostasis of calcium and phosphorus except hormonal regulations of PTH and vitamin D.
延伸閱讀
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