本篇報告三位不同類型之Horner氏症候群病例,包括中樞型(central)、節前型(preganglionic)及節後型(postganglionic)。有良性的病灶,也有危及生命的惡性病灶。有後天性的病因,亦有先天性病因。藉此三病例對Horner氏症候群之歷史背景、解剖學、發生率、症狀、病因及診斷回顧討論之。
Horner's syndrome is characterized by ptosis, miosis and facial anhydrosis. The syndrome is produced by a lesion occurring anywhere along the sympathetic pathway from the hypothalamus to the orbit. The pathway is generally considered to consist of three neurons. the central neuron, the pregangIionic neuron and the postganglionic neuron. It is ímportant to differentiate central, preganglionic and postganglionic Horner's syndrome sínce the preganglionic lesion is associated with malignancies in approximately fifty percent of patient while the postgangIionic lesion is almost always caused by a benign conditìon; thus, any pregangIionic Horner's syndrome without an obvious cause must be investigated thoroughly. The pharmacologic study is most often used to localize the lesion ínterrupting the sympathetic pathway. We report three cases of Horner's syndrome including central, pregangIionic and postgangIioníc Horner's syndrome. The clinic, anatomic, and pharmacologic studies of those lesions are discussed.