國人未成年者尿鈣排泄與尿路結石者之研究分析

過去10年由38家教學醫院所收集之266位20歲以下未成年之尿路結石者為分析之對象。其中男性多於女性（2.2:1），在臨床症狀中以血尿與腹部疼痛為主，而腎臟及輸尿管則是結石之主要部位。在266位結石者中，16-20歲者有200位（76%），而15歲以下者僅有66位（24%）。國人正常學生（7歲至18歲）1072人之尿鈣排泄之分析結果顯示；15-18者之尿鈣排泄比15歲以下者之尿鈣排泄有明顯之增加。這項結果或許即是16-20歲者為未成年之尿路結石者中之高發生率之重要危險因子。而該年齡層有明顯較高之尿鈣排泄之結果是否與其對鈣之需求減少、胃腸道對鈣的吸收增加或鈣在腎小管的再吸收減少等有關，則有待進一步之研究。

關鍵字

尿鈣排泄；尿路結石；危險因子

並列摘要

Two hundred and sixty-six stone patients under 20 years of age collected from 38 teaching hospitals in the past 10 years were analysed. The ratio males to females was 2.2:1. Abdominal pain and hematuria were the main clinical manifestations. The kidney and ureter were the main sites of location of stone formation. Among 266 stone patients, 200 (76%) were 16-20 years of age, and only 66 (24%) were less than 16 years of age. The study of urinary calcium excretion in normal children. In 15-18 years old children fasting Ca/Cr ratios and 24-hour urinary calcium excretion were statistically greater than in the two younger age groups. Increased urinary calcium excretion in the 15 to 18 years old children may represent a potential risk factor for the increased prevalence of renal stone formation in children 16-20 years of age. Whether this unexpected finding related to a different calcium requirement, increased gastrointestinal absorption or decreased renal resorption of calcium in the 16-20 age group cannot be answered by this study. Further investigation is needed.

並列關鍵字

Calcium excretion ； urolithiasis ； risk factor

國際替代計量

國人未成年者尿鈣排泄與尿路結石者之研究分析

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