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Inappropriate Secretion of Antidiuretic Hormone with Severe Hyponatremia in Sheehan's Syndrome

席漢症候群合併抗利尿劑不適當分泌致嚴重低血鈉症-病歷報告

摘要


一位36歲之女性,十個月前曾剖腹生產大量出血致休克而被大量輸血急救。此後病人自覺身體狀況大不如前,住院時意識不清,且有噁心,嘔吐,無力等症狀,經實驗室檢查證實是席漢症候群合併抗利尿劑不適當分泌致嚴重低血鈉症。使用類固醇,左旋甲狀腺素,高張性鹽水等治療,很快改善低血鈉症,且臨床症狀也有明顯的進步。席漢症候群在臨床上常見多重性的症狀與徵象,但造成低張性低血鈉症尚屬少見,需與其他的低血納症做鑑別診斷,故提出此一病歷報告。

並列摘要


A 36 year-old woman experienced a hemorrhagic shock after C/S delivery ten months ago. She was seen in an obtundent consciousness, nausea, vomiting and weakness when she was sent to N.G hospital. The results of laboratory evaluation were consistent with the inappropriate of antidiuretic hromone secretion caused by hypopituitarism. Therapy was done with hydrocortisone, hypertonic saline and Levothyroxine which rapidly corrected hypotonic hyponatremia. The hypotonic hyponatremia caused by Sheehan's syndromne should be considered in the differential diagnosis of other causes of hyponatremia.

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