廣泛性新生兒腸病毒感染－一病例報告

非小兒痲痺型腸病毒感染在幼兒時期相當普遍，特別在夏末秋初為流行季節，臨床上症狀多半輕微而且無明顯後遺症。但是在新生兒期感染腸病毒，尤其是在週產期時得到感染，在臨床上所表現的症狀往往非常嚴重，而其臨床症狀與新生兒細菌性敗血病不易作鑑別診斷。本院報告一嚴重新生兒腸病毒感染的病例，臨床上出現雙相性的症狀。起先病患以發燒、食慾變差等非特異的臨床症狀的表徵，於數日後才出現散佈性血管內凝集病變等嚴重症狀。病患接受保守性治療後臨床症狀逐漸恢復，於出生一個月後出院。關於此病例，我們探討其病程並對最近處理趨勢做一文獻回顧，讓所有醫師在流行季節能對此疾病有所認知。

關鍵字

新生兒腸病毒感染；雙相性；散佈性血管內凝集病變

並列摘要

Nonpolio-enterovirus infections are extremely common in young childhood. Enterovirus infections are most prevalent during the late summer and early autumn. Most enterovirus infections are either asymptomatic or cause simple febrile illness without complication. However, infants infected in the perinatal period developed severe often fatal diseases. The clinical manifestations of neonatal enterovirus disease are relatively nonspecific and are encountered with a similar frequency in neonates with other viral or bacterial sepsis. We report a newborn with severe enterovirus infection who had a typical biphasic presention in which non-specific symptoms precede clinical evidence of disseminated intravascular coagulation. After conservative treatment, the infant improved slowly and was discharged on the 30th days after birth. We presented the case for emphasizing the importance of neonatal enterovirus infection especially during seasonal prevanlance.

並列關鍵字

neonatal enterovirus infection ； biphasic phase ； disseminated intravascular coagulation

國際替代計量

廣泛性新生兒腸病毒感染－一病例報告

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