Primary Papillary Adenocarcinoma of the Rete Testis: Report of a Case and Review of Literature

原發性睪丸網乳突腺癌極為罕見，通常易誤診為轉移癌。文中報告一七十五歲男性因其睪丸數月以來逐漸漲大，但並不覺得疼痛。至本院手術摘除並經病理切片鏡檢、免疫化學染色、及電鏡研究後確認為一極為罕見的原發性睪丸網乳突腺癌。此案例雖經手術治療及追加局部放射線治療，仍然在術後二十五週出現陰莖根局部皮膚轉移，二十八週出現腹水。據國外文獻報告此病一般預後不良，通常在診斷後二至十月內即死亡。很不幸的，此病例雖合病化學治療，仍於術後四十二週因此病死亡。

關鍵字

腺癌；睪丸網；轉移癌；免疫化學染色；電鏡

並列摘要

Primary papillary adenocarcinoma of the rete testis if extremely rare and may be misdiagnosed as a metastatic carcinoma of the testis. A 75-year-old man was admitted due to progressive, painless, enlargement of his testes for several months prior to his first hospitalization. Bilateral orchiectomy was performed and confirmed to be a case of primary testicular cancer. The tumor cells manifested a transition to the normal epithelial cells of the rete testis. They grew in a papillary pattern with delicate fibrovascular cores and occasional psammoma bodies. By immunohistochemistry, this tumor was positive for carcinoembryonic antigen and cytokeratin, but negative for thyroglobulin, alpha-fetal protein, or placental alkaline phosphatase. Electron microscopy showed short microvilli of cytoplasmic border and invagination of nuclei. Twenty- five weeks after orchiectomy combined with local radiotherapy, tumor metastasis to the penile foot skin was noted. Malignant tumor cells in ascites were found at the 28th weeks of hospitalization after first surgical therapy. He was dead from the tumor at the 42th weeks after surgery.

並列關鍵字

adenocarcinoma ； rete testis ； metastatic carcinoma ； immunohistochemistry ； electron microscopy

國際替代計量

Primary Papillary Adenocarcinoma of the Rete Testis: Report of a Case and Review of Literature

全文下載

主題瀏覽