The purpose of this descriptive study is to investigate the changes in fatigue and its related factors of patients with breast cancer before and after chemotherapy. The subjects consist of 109 breast cancer patients receiving chemotherapy at the three medical centers in Taipei. The instruments included the Piper Fatigue Scale (PFS), the Schwartz Cancer Fatigue Scale (SCFS), the Symptom Distress Scale, the Mood Disturbance Questionnaire, and the Eastern Cooperative Oncology Group performance status. The main results are as follows: (1) Fatigue significantly increases after chemotherapy in comparison to the situation before chemotherapy (p<0.001); (2) Fatigue significantly relates to symptom distress, mood disturbance, and functional status (p<0.001). Previous medical disease history and chemotherapy regimens administered are also significantly related to fatigue (p<0.05). Further stepwise regression shows that both symptom distress and mood disturbance explain 5 1.8% by PFS and 64.2% by SCFS of the variance of fatigue. In conclusion, fatigue occurs significantly after chemotherapy for breast cancer patients and symptom distress, mood disturbance, and functional status are the related factors.
The purpose of this descriptive study is to investigate the changes in fatigue and its related factors of patients with breast cancer before and after chemotherapy. The subjects consist of 109 breast cancer patients receiving chemotherapy at the three medical centers in Taipei. The instruments included the Piper Fatigue Scale (PFS), the Schwartz Cancer Fatigue Scale (SCFS), the Symptom Distress Scale, the Mood Disturbance Questionnaire, and the Eastern Cooperative Oncology Group performance status. The main results are as follows: (1) Fatigue significantly increases after chemotherapy in comparison to the situation before chemotherapy (p<0.001); (2) Fatigue significantly relates to symptom distress, mood disturbance, and functional status (p<0.001). Previous medical disease history and chemotherapy regimens administered are also significantly related to fatigue (p<0.05). Further stepwise regression shows that both symptom distress and mood disturbance explain 5 1.8% by PFS and 64.2% by SCFS of the variance of fatigue. In conclusion, fatigue occurs significantly after chemotherapy for breast cancer patients and symptom distress, mood disturbance, and functional status are the related factors.