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Intrathoracic lymphadenopathy is a common disorder that may be benign or malignant. Cervical mediastinoscopy and anterior mediastinotomy are common approaches to diagnose mediastinal lymphadenopathy. However, there are limitations in access to lymph nodes in the anterior mediastinal, posterior mediastinal, subcarinal and hilar areas. Nodal sampling by VATS has proved to be a valuable diagnostic approach for the assessment of lymphadenopathy that is inaccessible by cervical mediastinoscopy and mediastinotomy. A 48-year-old man presented with cough and chest pain for one month. Contrast-enhanced computed tomographic (CT) scan of his chest showed enlarged mediastinal and hilar lymph nodes. A hilar node was taken through video-assisted thoracoscopic surgery (VATS) and was proven histologically to be sarcoidosis.

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