- 期刊
- OpenAccess
Cognitive Function, Depressive Symptoms, Function Level, and Quality of Life in Mild Dementia and Amnestic‑mild Cognitive Impairment
並列摘要
The present study aimed to investigate the relationship among neurocognitive variables, depressive symptoms, functional activities, and the quality of life (QoL) in patients with mild dementia and single-domain amnestic mild cognitive impairment (a-MCI). Materials and Methods: Thirty-seven mild dementia patients and thirty a-MCI participants were recruited. All subjects participated in a series of neuropsychological measures (Cognitive Abilities Screening Instrument, family pictures, and digit span), geriatric depression scale‑15 (GDS-15), activities of daily living (ADL), The Lawton instrumental ADL scale (IADL) and QoL‑Alzheimer’s disease. Results: Multiple regression analysis revealed that only depressive symptoms was a predictor for the QoL in mild dementia (β= -0.56, P ＜ 0.001). In contrast, all variables were not associated with the QoL in a‑MCI. Mildly demented people scored significantly lower on most aspects of cognitive functioning and reported poorer performances on IADL than a-MCI. There were no significant differences on GDS, ADL, and QoL between the two groups. Conclusion: Findings indicated that depressive symptoms contributed to the QoL in mild dementia. Interventions targeting depressive symptoms in mild dementia may improve their QoL during their early stages of dementia.
延伸閱讀
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